Christopher Greene, the son of Nathanael Greene and Mary Mott, was born on 23 July 1748 in Potowomut Neck, Warwick County, Rhode Island. Christopher served as a member of the Committee of Public Safety in Rhode Island. He was one of the earliest commanders of the Kentish Guards of East Greenwich, Rhode Island Volunteers, which corps he helped to organize in the year 1774. He took part in Sullivan’s Expedition on Rhode Island, in which he occupied an honorable command under his brother, Major General Nathanael Greene. He was also a member of the Rhode Island state convention which ratified the Constitution of the United States.
Christopher Greene married Catherine Ward on December 23, 1773, and they had two children: Anne Greene (1776), and Catherine Greene (1780). Following her death, he married Catherine’s sister, Deborah Ward, on May 5, 1783, and they had eight children: Christopher Greene (1783), Celia Greene (1786), Emily Greene (1787), Nathanael Greene (1789), Richard Ward Greene (1792), Samuel Ward Greene (1794), John Ward Greene (1795), and Elihue Greene (1802).
Christopher Greene was involved in the family iron manufacturing business at the Forge at Potowomut. He also went into business with his brother, Elihu Greene, in the E&C Greene mercantile company. Christopher died on 22 December 1830 in Potowomut, Rhode Island, and is buried at the Old Forge Burying Ground in Warwick, Rhode Island.